My USB Apollo would throw a massive fit. It cannot handle a complex track lay out with multiple effects. It breaks up. I can record with the Apollo ASIO and switch to ASIO4ALL and do a bunch of VSTs. The Laptop does it fine. Most of my recording use a minimum of effects and VST for this reason.
Great idea , I d love to make some sub groups.
Sorry, but that makes no sense. Your interface has NOTHING to do with number of tracks/groups/Plugins/etc unless you are using the built-in FX in the AI itself (just turn those off and use the ones in Reaper!) That's ALL a function of your computer. In Reaper, putting tracks into a group folder uses NO computer resources.