Hazard Nova
Everything in moderation
Get an interface and start recording/learning. There is no 101, rule book or anything else that'll really help you. Record a track and then record another, experiment, mess with the sounds until you get what YOU like. Picture it in your head and hear it before you lay it down. Does the track want 1 guitar or 4? Only you will know. Don't think for a minute you have to have X amount of layered guitars to make it sound good. Most of the time, less is more!
Someone could give you the amp, comp, eq, delay and reverb settings for a nice sound for them. Doesn't mean it'll work for you. No one has been to the Multi-Layering Guitar Tracks school. It's all about trial and error. If you think there is a magic formula or plugin to make it happen, you're very much mistaken.
Time for you to start playing and learning the craft, from the beginning. No two ways about it. (As it would be for anyone else stumbling upon this thread)
Right, that's been made very clear. But some of the advice (for example, back off the gain if you're going to layer multiple overdriven tracks) seems pretty universal. It's also something that might have taken me a few days to figure out. Now I've been saved that time--and so have other people who might read this later.
But yes, I'm counting on having to experiment on my own and find my own sounds and preferences.