i use clayton .63's for most of my acoustic work-they seem to be the proper middle ground between hard and soft, for extended dynamics-if i want a less yielding pickstroke, i use it perpendicularly ot the strings.
for electric, i typically use "something heavy"-i have heavy dunlops (mixed opinions on the feel of various kinds there-i tend to like a smooth pick feel), heavy pick boys (studded, and "stubby" bass picks), a stainless steel pick, some others, and some picks i made myself with a hammer and a coin, just hammering them out flat on conrete, then sharpening with a knife sharpener (and they're SHARP!)-they were neat, but i don't use em much anymore-think i took out strings pretty easily with them.
i NEVER, EVER use fender picks, even though i think the feel and design aren't too bad-if i play hard for an hour, they'll be largely destroyed, and smell like pine trees(and they get hot, too)-crappy materials, in my opinion.
any other suggestions for long-lasting picks in the general medium range?