The better ones.
Seriously - It depends on so many variables...
I like "real" speakers - If it says "Studio Monitor" on them, you can throw them in a pile and light 'em up.
But that's me. "Studio Monitors" are what we used to check mixes on to see if they sucked on small, bad-sounding speakers. Now, people use those same small, bad-sounding speakers as their mains.
But for what they're designed for - Short-throw, narrow dispersion... If you need to take the room out of the equation, they'll certainly give you better results than a large set of full-range boxes.
But for YOUR room... It depends on what your room can handle. If it's fairly small, maybe go with something in an 8" woof and nix the sub. You can always add it later. And of course, anything you can do to treat the room to make it sound better is always a plus.