I'll jump on this thread... I have been absent for years but I use:
Mackie 32X8bus board which is extremely versatile. It's really 64 channels thanks to the Mix-B function. I know mackie gets a bad rap but I like the pre-amp although I do have 4 outboard preamps as well that go into a patch bay and get directed into my converters. (however the monitoring shows up on the mixer).
So when I track I use the Input channels for tracking either by way of sub busses or direct out (usually direct out) to 16 channels of AD conversion by means of a pair of RME ADI-8's.
Then I mix in Nuendo.
Send it back out through the DA part of the RME's to the Mix-B inputs on the board. It allows for extremely versatile monitoring (pretty much overkill). I had the board for years before I actually read the manual. I was using only half of the functions.
It really is an excellent board but then again many people have more knowledge than I do.
Built in Talk back, headphone amp, mix-b, control rooms, mains. It has everything you need. I also have the metering bridge which is probably not as useful as the meters on Nuendo but still looks pretty.
Although all of this stuff is sitting in storage until I finish building my new basement.
I mix in the box though and need to find some control surfaces to use but I'm also a perpetual novice so I am usually a little behind the times. I liked the Tascam 24 channel one they had but I don't know if they still make that. Also for mixing, i don't mind the mouse so much, but I need the dual video monitors. Once you go with a dual display you cannot just go back to one.