Usually, but it will also change the sound.
Like guido said, flip the saddle. If that is impossible with the bridge you have, you can remove the saddle, and file down some of the metal(if it needs to move closer to the neck), just make sure not to file on the grove. The depth of the groove should be half the thickness of the string you are using. if the saddle needs to go further back, you can file some of the metal off the very back of the saddle, thus allowing the saddle to go further back. make sure you dont dig into the groove, nor take too much metal off, causing the screw not to be able to secure the saddle itself. Also, are you sure that the string hieght is where it needs to be? Had a prs brought to me after it went through a few shops, and they could not "fix" it. They were actually suggesting the frets be filed down a bit. I made a very light adjustment to string hieght, and made sure the contour was proper for a compound radious neck, and the thing rocked!!!!