And in some ways I take the opposite opinion of jimistone. I think Epi's make great distortion, but not that cold distant distortion. A good contrast is "Whole Lotta Love" done on a Gibson, and "Achilles Last Stand" done on Fender. Plus, GnR's Slash has a tone that I consider "classic rock" because if its bluesy warmth. Slash played an Epi on Appetite for Destruction.
Either way, from a recording standpoint, whether you want an Epi or Strat depends more than anything on the song your recording. From the way I hear music, a song that has an urban feel to it, or something with a bit of Jeff Beck-styled night boogie begs for the use of a strat sound. A song that's supposed to be heard when you are getting drunk in bars, or hanging out with a coven of witches makes the darker and warmer tones of a Gibson or Epi the better mode of expression.
Confused yet or no?
Cy