I have no clue what you mean by an "inappropriate load presented by the preamp". If you are referring to having too hot of a signal going to the preamp, then that's possible. How loud is the amp? Most mics can easily handle around 120dB or more. If there's a 10 or 20dB pad, it can go even higher. Now, if you are blasting the mic and have the preamp input too high, you're probably clipping the signal. It should show up on the interface. In that case, a simple turn of the input level should fix it.
If your input is going into the DAW too hot, it will show up as clipping, which is very easy to see in the waveform, and sounds like crap, often as a crackling sound.
What interface and mic are you using? How loud is your amp?
The other possiblity is that the mic is simply picking up sounds that you aren't hearing in the room.