Here's what I do...
Hi all,
Here's how I do it: I first fiddle with Reason and get the sounds I want, then I dump it all into my Korg D1600. Then I playback on the Korg and record the guitar or bass or whatever. I'm going S/P DIF on the transfers so there is no loss in quality.
Anyway, my friend is set up on Pro Tools and he uses Reason rewired to Pro Tools. It seems kinda hard doing it that way, but then again that's just me. I'm too used to working with my Korg. I still like using actual pieces of gear whenever possible.