And, in response to the question that wasn't asked...
If you have single 1/4" "insert" jack (as is quite common), it uses a TRS plug, but it carries two separate unbalanced connections. This is done by what is commonly called the "Tip Send/Ring Return" format. The tip and sleeve form one unbalanced circuit, which is connected to the input on the external gear, while the ring and sleeve form the other unbalanced circuit, which is connected to the output on the external gear. Hosa and other companies sell 1 TRS x 2 TS cables, and 4 TRS x 8 TS snakes to ease these connections.
But you have to remember that you may be connecting to balanced I/O on the external gear and may
need to compensate for level differences that may result, although some gear now does this internally.
This can also complicate things is you're running through a patch panel as you may have balanced and unbalanced jacks in the same row...