Mainly I use drum samples from Reason 4 but I will use anything if it fits.
One night I used a synth as a bass bed then piled on sampled drums, piano, sax, flute, B3, cellos, vibes, and strings. It was a self challenge to play a different instrument on each pass and fill a different spot in the tune; it turned out pretty well.
I’ve also written orchestral music with Garritan Personal Orchestra – some fine samples in that program.
They’re just sounds to be used at my whim.
I’d use auto tune too if I had it.
To me it’s the same as love and war – all’s fair. I let the ideologues yell about it.