Yeah it's possible with a generic remote device or a midi panel (which is a little harder to program), just use the generic remote device and send whatever midi notes or CC's you need to control the hardware.
Create some midi channels / faders to assign them to and drop them in a folder.
No, I do everything in the box but I think it's a cool feature to have for someone that can make use of it. I've thought about trying to use MIDI to change my controller's velocity curves when switching between vstis. It seems a like it would be a little involved, if even possible, so of course I haven't gotten around to it.