There's a difference not only in the quality of the media used on commercial CDs and most of the low end CD-Rs you'd buy at Walmart or wherever, but there's also a difference in the process of making the CD, including making a glass master that the CDs are manufactured from. There are places that will sell higher quality media, but without having a run of CDs manufactured, all home burned discs could potentially have a problem with certain CD players. Buying high quality CD-R will lessen the chance of this happening quite a bit though. If you are making CDs for distribution yourself at home, which I'm guessing most of us making CDs on this BBS either have done at some point or are going to in the future, there could be a loss of quality and life of the finished product. Not sonic quality, but media quality I mean.
Friend of mine had 50 discs burned by someone where he works in a machine that does 50 CDs in a batch type process, burning one after another until 50 copies are made. Half of those are now either completely bad, or they just don't play in certain computer CD-Rom drives. By the way, I hear of many computer CD drives not playing certain inexpensive media, especially laptop drives, and not as much about audio only CD players having problems.