No, I mean I usually plug in my guitar to my effects deck and that stright into the line-in or mic-in on the sound card. Very basic.
I don't have any recording equipment apart from my PC, my Sound card and cubase.
But someone told me I could plug my guitar into my guitar amp, and use the headphones out on the amp to plug into the sound card line-in. I tried it and I got no sound at all.