Ok, I think you need some basics!
Fruity loops is a mix of sampler, sequencer, and synthesizer technology. First, some definitions:
Sampler: a device that can record and playback audio samples. Often times it can tweek the samples in certain ways...like stretching or adding effects.
Sequencer: a device used to trigger other devices, like samplers, at specified times.
Sample: a pre-recorded audio sample, like a drum hit, usually triggered by a keyboard or sequencer or combination of the two.
Synthesizer: a "generator" of sound, usually triggered by a keyboard or sequencer or combination of the two.
Fruity loops is a sequencer that can be used to trigger samples or synths. It works usings patterns, or groups of patterns aranged into songs or parts.
When you start fruity, you're presented with a blank pattern, pattern number one. You'll see a number of channels representing the default synths and samples that fruity creates for you. Each tick in each channel represents a time at which you can trigger the synth or sample used by the channel. If you click the 4th beat on channel two, then when you hit play, the fourth sample on channel two will be triggered.
Now, if you require your synth or sample to play different "notes", then that's when you want to use the piano roll editor. The piano roll editor works very similiarly to the regular beat editor, except that where you click vertically determines the pitch of the note that will be produced.
With that information, fire up fruity loops and start making noise with it. Once you've made noise for a good hour or so you'll have most of it figured out, it's that easy to use!
Slackmaster 2000