Figure out what you want to use the guitar for - that'll help you with the Dreadnaught / Grand Concert / Classical  / OM style set of issues.
Then choose your price range - everything is relative in this business. I'd look for the basics - solid top (!!), Solid woods all through if you can get them, good fit and finish, no overfinishing, good intonation, decent tuning machines - and eliminate a bunch of models based on that. 
You should be able to find a really nice acoustic instrument that will sound good on or off the track, so to speak, for something in the $800 range (and up). Alvarez has models in that range - as does Tacoma, Guild, Seagull, Epiphone, Carvin, Fender, and so forth. Most of these are Korean factory guitars built to brand specs (but not all!! - look at the Tacomas - the company is Korean but the factory is in the States. Seagulls are built by  La Si Do - parent company to Godin - and one of the largest mfr of guitars on the continent -  Canadian) and they are at a ferociously competitive price point - meaning you can get more for your money here, not less.
Go down a price point - the $300 range - and the reverse is true. It's a seller's market and you will be frustrated unless you're lucky.
The over  - $1000 market is also fiercely competitive, but here you will find instruments beginning to open up and show individual character - and the occasional cannon waiting for you to stumble onto it.  
Higher - well, the sky is the limit and the customer gets very picky up in the stratosphere.