Lead vocal needs a bit more presence in the mix - sounds distant - and I'm not a huge fan of some of the performance either, especially in the quieter bits where he sounds a bit like he's got a peg on his nose. Could be a mic positioning thing perhaps?
Ever hear the singer from The Afghan Whigs? Can't sing on pitch to save his life, I reckon, but it all works... Don't think your man's quite there yet.
Greg's right about the lead guitar bending notes... they're often just a bit flat or a bit sharp - you may, just may, be able to touch them up with an autotune if you're committed to them, but there's a bit of that not quite pleasant distortion happening that you get from either not having enough saturation or not having good kit.... but if it was me, I'd be retracking them with a bitier, less distorted, middier sound myself, but your mileage, as they say, may vary...
What guitar and amp are we talking here?
Song has promise however. Keep working at it. Just my $0.02