Ok, I think it's time for someone who deals with this stuff for a living to step in. To answer the question: You might possibly, if you're using a VIA chipset motherboard. BUT! The same goes for an Intel Processor with a VIA chipset motherboard (and yes said motherboards exist, abeit rare.) I believe you said Viking 3 chipset...probably not. An Athlong will definitely give you computer problems if it's a Via chipset motherboard (KX133, KT133...) but doubtful if it's an AMD750/AMD760 based motherboard. The incompatibilities do not exist so far as the CPU is concerned, it's the danged chipsets! Via has some warped philosophy(I don't know it, so don't ask me to tell it to you.) on dealing with PCI and plug-n-pray. Card manufacturers could get around it with drivers in most cases, they choose not to however. Most people will have no problems or few problems with AMD based systems, just watch your motherboard you buy. To the fellow who mentioned setup problems with his Midiman...you prolly would have were it an Intel chip. I'll be honest, if you're looking at speed and games...best platform is the AMD Thunderbird. (Or Duron if you're poor like me. ;-) For us audiophiles dual-Xeon's with Win2k just can not be beat! Dual CPUs SHOULD produce lower-latency, and fast DSP.(this is speaking strictly on PCs of courses, MACs are better for multi-media, period, especially G4s.) Anymore questions?