I don't even know what the spacing is on my guitars.   
I have one of the Vintage54 strats,   The radius is 7 1/2 inches, but I dont know about the spacing.  I know it doesn't give me a problem playing.   I have an ASAT Special and an old G&L Legacy.  Flatter radius, but I don't think they are much different from the strat.
The biggest change is when I pick up my Taylor 310ce.    Its got a really wide fretboard which is fine for fingerpicking, but not as comfortable or easy to do things like barre chords.  
I seem to adjust to things like spacing and radius but I really hate the necks on PRS guitars.   Something about the back shape doesn't fit well for me.   Its especially bad on the SE models.