I am just getting started with the US-122 and enclosed Cubase, and I'm not having much luck. I'm running a P3 600mhz, 256 RAM, fresh install of 2000 pro, my chipset is one of the five or so reccomended in the owners manual, and I can't get anything down without the skipping cd effect. I've done a little research which led me to shut down all unneeded stuff in windows(like screensavers, desktop, background, sounds, etc.), I shutdown my ethernet card before launching Cubase, I've installed a USB 2.0 card dedicated to the US-122 (and no other USB devices are plugged in anywhere), I bought a powered USB hub, I've tried different USB ports, and I'm still not making music. I wondered about installing XP, or maybe more RAM, but I tend to think this may be a power issue- I haven't had the guts to try a condenser mike yet, as I figure it will only make it worse. Has anyone else ever had to go this far with the 122 to get it up and running? Any thoughts?