The vocal sounds like it's coming through a doorway to a big empty concert hall while the picked guitar sounds like its amp is right next to me, in terms of volume, tone and reverb. The drums sound like they're in that other room with the singer. Try getting a solid mix with just drums and vocal, keeping them nice and clear, then add the bass, then fill in around them with guitars.
The voice is doubled, right? I'd pick one to be the lead and place it center. Then set the other one back a touch and do a high shelf cut from about 3kHz up, panned just slightly off center if panned at all.
Horns might be cool, but keep them subdued so they don't step on the vocal.