Well,
listen to this track ("Hunter" by TeeBee, one of the best Drum and Bass acts in the world).
Drum and Bass is an electronic dance music form, and as the name suggests its main elements are drums and bass. Everything is (almost always) electronic, based on drum loops, and a heavy use of samplers.
There is no way anything in this track could be done by conventional-stick a mic and record-way. I especially want to bring your attention to the main melodic "bass" line, the way its timbre gets twisted around through some heavy and very intricate filtering. This kind of sound doesn't exist in the "natural" or acoustic world, however it does come
naturally to some samplers.
While I can understand that many on this board view samplers as a way to imitate (and in many cases poorly) other instruments (strings, pianos, etc...) and thus refer to them as "not real instruments" or "artificial" however, that's a very limited view because most of you are missing the point of those electronic instruments.
The above example is a perfect illustration of my point because it uses the sampler as an instrument in its own right. The main sound (and many others) is not trying to imitate anything else. It is it's own entity. It is "naturally" electronic in it's best sense of the word as it wouldn't be possible to get that sound any other way.
We can argue about the drum loop, however, you'd be hard pressed to get that particular sound by recording an actual drum set with an actual drummer. Yes, there are drummers that have no problem playing the drumset in the 165-180BPM range of Drum and Bass, but it wouldn't sound the same. The drums in the above recording are obviously sourced/sampled from a recording of actual drums, however they have been processed, pitch-shifted, sped up, layered with drum hits from other samples, to make a sound that is obviously electronic.
In conclusion, what I am getting at is while I can understand why some of you refer to sampled sounds as "artificial" because you are only referring to instances where you are imitating an instrument (mostly poorly) that could be recorded with mics and all that, and the most usual victim of this approach is the drumset. However
because you view the sampler only as an "imitator" you are failing to see the larger picture, and failing to realise that the sampler itself is a very powerful instrument in its own right, as it is capable of producing unique sounds that only can be done through the use of the sampler.
Rami's post is most telling, where he's "proud" that he doesn't use samplers, sequencers and other electronic stuff. Well, that's because he's doing rock and that genre, let's face it sounds really "fake" when you substitute real drummer with a drum machine. However, I say listen to Rammstein for some very fine use of samplers and synthesizers in heavy metal/industrial rock music.
However, I am sure TeeBee is very "proud" of that twisty sound that he came up with through the very creative use of his sampler.
Again, my main pet peeve is this limited and skewed viewpoint of seeing electronic instruments only as imitators, rather than instruments in their own right.
Use each instrument for what it is, instead of trying to make an instrument into what it is not and then dismiss it because it "doesn't sound natural", because it WILL sound fake.