I think we need a little more information. Are you talking about ambient noise due to a air movement from a fan? Are you talking about a ticking sound in ambient that is produced by your computer's switching power supply? Or, are you talking about in-band noise within the channel?
As Rusty said, are you connecting your PC via a proper digital interconnect such as USB? Or, do you have a pop-hiss-buzz-hum emitter stemming from some analog contraption you have implemented?
Give us some facts man, and in turn we will give you thoughtful analysis or a smart ass opinion, or some combination of the two.
Either way, your problem might get solved.