I'd say if you have the gear, whether high or low end, try it and see if you like it and if it does anything for you with your set up. There are tons of opinions about the quality of conversion etc etc etc and why you shouldn't do it unless you have the proverbial $64000 converters but I call BS on that.
IMO If anything but the worlds best converters are so bad at converting, the defects would be immediately obvious in any recorded sound. My reasoning is: I trust my converters to adequately and accurately convert live A/D, I trust my converters to adequately and accurately convert D/A for monitoring and mixing. Yet I am often reading that I cannot trust them to adequately and accuarately convert a D/A back to A/D one time for re recording. I Say BS and I tested just the converters on my gear by running a mix straight out and back in again with nothing else in between and was not able to hear any difference at all (level matched and randomized on a play list so I didn't know which one was playing) I was also able to null the original and re recorded mix to the digital noise floor,
So at least on my prosumer gear I would say there is no problem with one extra A/D conversion.
Anyhow back to topic.
I have started to experiment mixing out of a profires 8 outs through a BLA summing box: tracks stemmed to 3 stereo busses gits, keys and effects (6 outs), 1 mono vocal and 1 mono bass channel (1 out each) and then a modified ART Pro VLA across the master stereo outs of the summing mixer before going back into the DAW for recording.
none of it is high end gear by any means and it certainly is different than mixing 100% ITB and it's been my experience that you have to mix through it from the get go to get any benefit, not just stick the OTB stuff in at the end of the mixing process. there's certainly learning curve for me but I'm enjoying the new process so far.
one thing I would say is that you should get yourself a multimeter and test your stuff so you know where 0VU is, on your output signal and how that translates on your DAW meters. I found on my gear, this can have a huge impact when you go OTB and really make or break the sound you get out of it depending on the "Heat" of a signal the outboard gear is expecting, how much headroom is available and what the OTB stuff does to the sound if you push into their headrrom (ie some stuff will intentionally color the sound and the harder it is pushed the more obvious that coloration becomes)