I don't know about USB, but I've used the Firestudio Mobile, which is a bus powered Firewire interface. It comes with an external power supply, but I've never really needed it. It doesn't put any stress on my laptop energy wise, and it doesn't slow it down or anything either if that's what you meant. I think the external supply might be necessary when using phantom power? I don't know, I have external pre amps for that so I've never tested that theory out.