I've always been curious about actually mixing substantially with the NS10s. I've heard them, and didn't particularly like their sound. Once I almost bought a pair, back in the early '90s...and the sales guy (who I dealt with before, and new his shit) said not to get them, and he suggested a pair of Tannoys, the small near-field kind (forget the model, to lazy to get up and look)...which I used for awhile, but didn't really love them either, and eventually the speaker surrounds fell apart, I got some different speakers, but with similar specs, and now they're sitting here in my living room, tied to the stereo system.
They sound OK. I took my 3-way Technics off the stereo system and moved them into my studio...just when I want the huge stereo speaker sound. They sit in the back of the studio, not at the mix position.
Anyway...I think you can get use to working with the NS10s...and I think what they are best for, is what Jay said...to bring out the mid-range, which is key area for Rock/Pop music...but in all the big studios, they have at least 1-2 additional sets of bigger/truer monitors, as I doubt you would want to mix more modern exclusively stuff on them....the stuff with the huge low end, and over exaggerated highs. You wouldn't be able to get that low end...and yeah, you would have to break out the tissue paper for the tweeters if you cranked the highs.
Still...I've always been curious about the NS10s....maybe just because they were such a staple for awhile there.
Not sure though if I would want to get anyone's used NS10s...so I may never know their appeal.
It's one of the reasons I also settled on the Mackie 824 monitors...because for awhile there, they were turning up a lot in big studios as a mid-field alternative, and also because they were designed to be super flat (your room permitting).
I liked how they sounded in my space when I first auditioned them, and I figured they were sorta one of the "approved" monitors for studio use...though after 10 years or so...I find myself thinking about something else, something at least one notch above the Mackies....and no, I'm not gear shaming the Mackies or the NS10s.