in some respects, your engineer friend is correct--it won't make as big a difference as if it were a preamp tube. (the SCXD and VCXD have solidstate preamps and a tube PI and power section) however, swapping the PI may help change the distortion characteristics somewhat. i wouldn't expect a dramatic change--but you might find things a little sweeter, gainier, whatever, depending on the tube used.
changing the power tube will also change the character of the amp somewhat, especially if you get it turned up to a point where it's really cookin.
always rebias after a power tube change.
as for what tubes? someone once said that picking tubes for someone's amp is like buying a shirt for someone you've never seen.
personally, i like the old ones. i'm a BIG fan of old RCA Blackplate and white-letter GE 12ax7's. As to 6V6's, i really, really dig the JAN (joint army navy) brown mustard base RCAs and the old circle logo smoked glass RCA Blackplates.
the RCA blackplate 12ax7s have a really nice high end--bright but not too strident coupled with an excellent low end. the GE's have a sparklier high end, not as much bottom....and more present mids than the RCAs.
a lot of folks will rave about telefunken 12ax7s as well.....nothing to complain about here. they're VERY hifi sounding to my ears.....almost to the point of being a little sterile. i like a lot of character in my amp tubes, and the teles i've used (both smooth and ribbed plates) aren't exactly what i'd consider character tubes. they're clean and smooth and more or less get out of the way of the amp, if that makes any sense.
i also like the made in holland amperex bugleboys. the ones i've used have been like a cross between the GE's and the telefunkens, but for the prices they go for, i'm not sure they're worth it. be sure that the ones you buy still read "made in holland", as "amperex bugle boy" is simply a relabelling (just like Groove Tubes), and "what's inside" can vary.
i haven't found a currently manufactured tube that i think can compete with old RCA and GEs in fender amps.....but the JJs aren't *bad*. of course, depending entirely on which JJ you end up with.
please understand that YMMV with tubes given their age, life left in em, and depending on the amp in which they're used. that said, i really think that if you were to outfit that thing with a nice set of RCA blackplates, you'll find things to be a degree or two of better.
cheers,
wade