Use the spdif optical connections, if that's what you're talking about. That and the midi connections of course. I'm not that familiar with Cool Edit, but with Cakewalk it's pretty easy. Set the computer as master, and the VS as slave. The vs manual should list the settings. Use midi machine control and midi time clock. I use an M-Audio Dio card for optical, and it came with a little synch program that matches the optical synch data. I tried a Gadgetlabs spdif card but I couldn't get rid of the static noise, so now I use both cards at the same time. One for audio and midi synching, the Gadgetlabs, and the Dio for spdif optical copying only. If you haven't done it before, you will get a headache. I had to do a lot of trial and error. Be sure to write down where all the settings in each unit are when it finally works. It's easy for me to hook it up now that I have the list to follow, and the sound is sooo clean. I'm using a VS880EX (20 bits), and the headroom after it's in Cakewalk (24 bits) is mind boggling. I'm using an older mixer on the computer output, and its inherent noisiness is pretty much non-existent. There’s inches of travel left on the output faders now, and added effects in the computer hardly use up any resources. I don’t do any editing in the 880, so it all goes to the computer, where the extra headroom is. And use a pre-amp on the 1680 inputs. Just last night I recorded a guitar track with the 880 inputs only, and then an identical track using an Art tube pre-amp, and the Art had a better overall sound. More definition and highs that didn’t come through without it. Sorry I got carried away and can't help specifically with Cool Edit Pro.