Yes and no... Yes, an audio cd (CD-AUDIO) must consist of 16-bit word length PCM data sampled at 44.1kHz.
The creation of the disc is another story entirely... There are a whole lot (a WHOLE lot) of programs that author CD-A discs NOT to spec. iTunes & WMP are the big two I see most. They might play, they might not. They might play on data drives (such as in a computer or many automotive drives that read data such as MP3 and WMA) but completely fail on a typical player (especially professional decks, such as those in performing arts facilities and radio stations).
Long story short -- If you aren't
100% certain that your authoring software is writing to Red Book specifications, assume it isn't. Burn discs, listen to them, pass them around - But don't even think of using one as a master disc for mass replication/duplication... The stories I could tell you about that...