yes it is different. I guess i did not asked the question correctly. So what i meant was, if there is higher noise floor or any other effect if you are operating +9 tape on a +6 biases machine. I understand that for sure you won't get any of the extra benefits, but vs. 456 on the same deck is there anything bad about it ? (other than no compression due to lack of saturation)
I've never actually tried it since I'm not into high output tape, but ...
I don't think you'd hear extra noise, since the tape is still operating at the same level (+6) ... you're just not taking advantage of the extra headroom. I've read elsewhere that some people like to run ATR tape at +6.
We should also make the distinction between 'operating level' (the 'volume' your deck is set up to operate at), and 'bias' -- which is the high frequency signal that is sent to stabilize the magnetic particles. People sometimes refer to 'bias' when they mean 'general calibration', which also includes things like adjusting your internal EQs as well.
The amount of bias required for different tape types is different. ATR is not a 'drop in' replacement for 456, regardless of operating level. Or rather, sure you can go ahead and try it -- and you might like the sound -- but it's not optimized to the correct standard. As far as I am aware, there is no +9 drop in replacement for 456.
For instance, Ampex 406 is 'bias compatible' with 456, even though it's a +3 tape. In this case, the operating level is different, but the tape is similar.
RMGI 911 is also considered a drop in replacement for 456 (though it doesn't quite sound the same). A tape like 468 is technically different, but I think sounds good on a deck setup for 456.
So you have more ideal options if are looking for a drop in replacement. Personally, Quantegy 406 and Scotch 206 are options I like. BUT ... you will get more noise and/or need to hit the tape harder, especially on narrow track decks.
THAT SAID ...
I've often just run any tape on any deck without calibration and it sounds cool. It's fun to play around with different tapes this way ... but it's a crapshoot.