I dont know about Mesa being in "stereo"....I think it has stereo inputs and two outputs but its not acually puting out a true stereo signal. (Unless its a new modeling amp)
The ONLY way I can think of using the stereo outs from the pedals to get a stereo sound is to have 2 amps. But to go from one stereo pedal to another you have to have stereo inputs on the receiving pedal. I have only seen expensive pedals with stereo ins. $300+ range.
I know a good multi EFX processor like a Lexicon would do exactly what you want, granted that you output to 2 amps. But in reguards to those who said that its not that big a difference...I record micing my Fender into my Roland 1680 and use a true stereo chorus into a true stereo delay into a true stereo reverb. If you can say flying high and swimming in the deep blue sea, then you might be able to almost smell how good it sounds.
For live I just output from the 1680 to a PA system and mess with audience. (I found most people who go to club shows haven't ever heard a nice setup, and are more interested if for no other reason than that.)
But if posed with mono EFX or no EFX, I just have to play dry, maybe some spring reverb from my fender.
But back to your question, there isn't much you can do with normal pedals other than mono link and stereo out the last one. If your amp does output in stereo and keeps the signal split up when its inputed, then thats awsome.