I used to work at apple tech support
Hey. A colleague. I used to work in repair here in Europe. But that's many moons ago. In the beige G3 era
USB can be confusing because of the way things are named:
USB 1.1 is max. 12 Mbit/s total or 6 Mbit one way and per device (full speed)
USB 2.0 is max. 480 Mbit/s total or 240 Mbit per device one way (high speed)
But they also support a low-speed rate of 1.5 Mbit/s, mainly for mice and keyboards. And USB 3.0 has several Super speed modi up to 5 Gbit/s.
If you connect a low speed and a full speed device on the same hub, they both will work at low speed. Some manufacturers (Apple) have extra ports (on the keyboard, for example) that only support low speed.
Most of the times, you don't know if the external USB ports share a hub or not. Better computers often have a hub per port, or one hub for ports in the back and another for ports up front. Often, not always. In fact, any config is possible. That's why using another USB port somtimes solves problems.
And audio is mostly one way, so the theoretical 480 Mbit/s is really only 240.
FireWire is simpler: 400 or 800 Mbit/sec, always available in both directions and to each device on the chain. It's also more intelligent, so it will put less strain on the CPU.
And than there's power. USB supplies 5V, 500 mA or 2,5 W which is plenty for a mouse or keyboard, but not so plenty for a big audio interface and certainly not enough for some harddisks. Result: kludges that use up 2 USB ports for an external bus powered HD. Firewire has at least 12V, 1.000 mA or 12 W.
To confuse things even more, there's also powered USB, USB-on-the-go and other stuff in the standard, but you'll see hardly any of those in audio.