cbas,
I have very similar goals to yours- just me, pod, guitar, drum machine, keyboard; ok, so I do own a tube amp, but just one, and it's small- although I do occassionly help buddies with recording their live bands. I would strongly urge you to go with at least 4 inputs. I started with a Roland VS-880 w/ 4 inputs and sometimes I wasn't happy with even that. Pod sounds best in stereo, ditto for my drum machine, and then if I want to sequence something stereo at the same time, that's six tracks- just little 'ole me. Sure you can do it all one at a time, and I usually do, but many times I need it all at once for maximum fun and inspiration.
As far as specific recommendations go, I looked at probably 10 to 15 candidates, made a chart with all the features as well as subjective opinions and finally decided on the Delta 1010- and the 66 was second. I think because of the higher than average dynamic range(although the importance of this at this level may be unimportant- they're all awesome, the 1010 just a little more so), number of inputs, and price, in that order. The only disadvantage is no headphone out. I usually just run the outputs to my monitor and headphones out of that.
I don't even own a mixer although a simple passive mixer would be nice. I can just run everything to the 1010. I usually leave the levels on max in the software, and control the levels at the actual equipment(pod or whatever)- it's all within arms reach. The only time I need a mixer is to record my buddies' bands. Sure, I'd like a mixer, but in the mean time, I'm enjoying
my Rode NT-1, SM-57, and BlueTube I could afford instead!