I've used fiberglass insulation in many of my panels--I strip off the paper facing and go from there. I'm always using Roxul now, going on the recommendations of people here and elsewhere. I believe Roxul is safer, though I've always handled glass wool with gloves, and of course I've always got the resperator on, even with Roxul. Once the panels are covered with fabric, and they are hung, it's all good. I've got two ceiling panels directly above the mixing point, with about 6 inches of clearance from ceiling to top of panel face. These panels are Roxul filled, though I don't think there is much difference acoustically speaking if one uses glass wool. I've got over 20 panels in the room now, including standing, folding panels that surround the recording areas. I've made some little 2' x 2' panels that I'm going to attempt to mount on stands that can be used for Reflexion filter-like sound deadening around mics, though the standing panels work very well indeed for this sort of thing now. At this point, Reflexion filters seem really pointless--I can see where they might be needed in a pinch, recording in a remote location or in an untreated room.