It's really no big deal. A few things to keep in mind:
- Static is an issue, but as long as you touch an unpainted metal part of the case before pulling out cards, you'll be ok. Don't shuffle your feet on the carpet between touching the case and removing the component though..

Handle cards buy there edges and try not to make contact with any of the IC's.
Some cases have a removable tray - so you can install the mainboard outside of the case, and then just slide it back. Can be easier, but not a critical feature.
- remove all cables, cards, hard drives, floppies etc. If you don't have some spare static bags to put them in in the meantime, place them on a piece of cardboard (low static).
Remove the motherboard
- Use a smaller screwdriver, most computer stuff is phillips(demagnetized, doesn't matter - I like one that has a slight magnetic pull to it, some of the mainboard screws can be tricky). When removing the screws on the motherboard, or anywhere else, try not to drop the screwdriver (i've done this a few times, with no bad result fortunatly), and be carefull not to scratch it. Usually 6 screws. Angle it slighly up when removing so that you don't scratch the bottom of the motherboard on of the riser posts below each screw.
- when putting the motherboard in the new case, no need to use 50ft/lbs of torque on the screws that secure it, just tight. In otherwords, don't over tighten. I've found with some cases it's difficult to handle the motherboard by the edges and still get the thing in, - if it's a slot 1 processor (or even ppga) you can hold on the top of the cpu when lowering the board into the case.
- keep ribbons and other cables away from the CPU fan - for ventilation reasons, as well as you don't want a ribbon to stop the fan. You may want to pick up some small nylon tie straps to neaton it up.
- Watch that the red strip on each ribbon cable is on pin 1 of the motherboard and pin 1 of the device it's being plugged into. On hard drives pin 1 is nearest the 5/12V power connector. On floppies, it's the opposite (99% of the time).
Outside of that, you should be fine. Just take your time.
[Edited by Emeric on 08-09-2000 at 09:21]