windowman, it would seem that you are making a career out of "guesses" around here.....
There IS no right answer to this question. There is ONLY what sounds good. PERIOD!!!
Now, the problem with assessing this question in ANY way is how do you get the same EXACT sound at the source between quiet and loud? You CAN'T! There is no way to make a source sound at a microphone sound the same quiet and loud. Too many other things come into play.
So, the right answer is:
Which way sounds better to you?
Indeed, the biggest issues involved here are:
Sound to noise ratio. Having to really boost the mic pre DOES effect the sound quality because it introduces much more NOISE. NOISE is NOT your friend in recordings (well sometimes it is...but that is a different story and explaination altogether...). And by the way mr.knowitallwindowman, the reason why compressors DON'T EVER go in front of a mic pre is because of NOISE. EVERY unit in a signal chain adds NOISE! It makes absolutely, and it NEVER has, to introduce NOISE BEFORE an amplification circuit, like a mic preamp. A mic pre is suppose to boost a very low voltage source into a higher voltage output. It hopefully will do so in a very linear manner (but even the best don't....they are just better than cheaper units....but cheaper units have their place in audio...), and hopefully, the pre will boost volume adding as little NOISE as possible to the signal. The more boost you need to apply, the more noise it applies. Now, why the hell would you want to run a noisy compressor circuit before a circuit that is going to amplify NOISE? Jesus....rediculous.
Next. Gain control Potentiometers tend to be very sensitive in their extremes. This can be problematic when the Pot. is doing something as sensitive as adjusting volume. Also, not all Pots. are perfectly linear in their taper. So, operating them in their extremes can prove to cause problems getting the right gain you seek. Most pots. and faders like to be ran in a certain "zone" per se, and you will get finer control in those zones. This is of little concern on preamps with fix gain stages, like a Focusrite Red.
Anyway, like I said earlier, there really isn't a "this is law" answer to this question, and well, it is sort of a stupid question!

But a very good stupid question actually that was good for the sake of discussion and learning about WHAT will effect the sound.
Eddie