I have to refrain from posting in the morning.
I read your post 'photshop , asus' and filled in the blanks with CUSL2-C, which is a different ASUS board and shouldn't have this problem, nor the TUSL2-C.
The TUSL2-C is a great board. I'd get one of those over the CUBX. I have built them for audio and used them for audio and they run fine.
It was the CUBX that gave me the photoshop grief. I did recommend the board at one point. Man, that was almost 2 years ago! I really can't keep all these names straight.
As for other problems with the CUBX, not that I'm aware of. BX chipset great and stable, but..... that was awhile ago, bit of a dinosaur now. Although, I'm still on the BX chipset, works well enough. I'm contemplating moving to AMD though as soon as more guinea pigs chime in.
Really though. The problem is obvious and easily reproducable. You
will have this problem with photoshop, unless the newest version has addressed this (but I doubt it, the problem is on ASUS's end).
Anyway, It's a decent board and I'm fairly confident it will work well for audio app's. (But if it doesnt, don't blame me

).
Do you have a chip for it? I can't remember what chips it supports but it's getting very difficult to find celerons or PIII's in the sub-1GHz range.