Extreme Static w/ Any Interface

[skinni]

Hey guys! I am running Cubase Elements 6 on my MacBook Pro 10.9.1.
I've been using it without problem for a while, but recently when I switch to a USB interface (I haven't tried firewire) the input signal becomes maxed out with static and hissing. I've tested the interfaces on other software and other computers and they work fine there.
I've uninstalled and reinstalled cubase with no luck. Is there something I'm missing?

Thank you, any help is awesome!
Jacob

 

[JimmyS1969]

What interface? Have you downloaded/installed the correct driver for it?

 

[skinni]

Thanks for the message!
Mac OSX 10.9.1
Presonus USB Audiobox // ZoomH4N (I've tried both)
No driver necessary for either. Problem doesn't exist in Garageband, Abelton Live, System preferences, anywhere else the interfaces work fine. Not cubase though.