If it doesn't explicitly say that it is Oxford 911, then assume that it is not. Yes, I would strongly recommend that you stick with the Oxford chipset, as there have been known issues with others. If you daisychain your drive and soundcard, then yes, speed will be affected. There is only 400Mbps of available bandwidth on the firewire bus and that must be shared between all devices on it. With USB2.0, you may end up with those blips in the sound...that has been my experience.
I have a Motu 828mkII firewire audio interface and a WiebeTech Firewire400/800/USB2.0 enclosure and what I did was run my Motu into my computer's existing Firewire 400 port, and then get a separate Firewire 800 card for the drive enclosure.
The type of drive you will be using will not matter. Even at the speed of Firewire 800 (800 Mbps = 100 MB/s), the firewire bus is still slower than your basic ATA133 IDE hard drive. I went ahead and got an enclosure that supports both IDE and SATA incase with the growing prevalence of SATA drives they actually become cheaper than IDE.