Well d-sub are not strong enough to hold that massive 16x3 multicable... for example.
Harting was just an example, they DO make audio connectors (industry, circuitry, audio.. what's the difference?)
If it's for permanent use, well than any connections would suffice.
But with cabling to be dragged around with and be (re)connected few times a month (for pa for example, or portable boards) you must have solid connectors.
There are many type of connections around, a standard d-sub is a cheap sollutions which will do the job at the end.
good luck finding the connector that suits your needs.
ro