Hi all--just a bit of clarification. DI, which stands for Direct Injection, is a device made to take a signal source, usually a high impedance (guitar) or a line source and then convert that signal to a line (+4) or low impedance (mic) signal that is balanced. This allows one to send a specific signal and INJECT it DIRECTly into a recording console. SOME DIs allow you to take the speaker signal from the power amp, but be sure the DI you are using allows this. There are guitar amps with a DI built in and send a very nice signal to mixers. Line outs on guitar amps are for sending a preamp signal to an effects processor. Now, this can be used to go into a mixer, but unless your amp has a built in cab and speaker emulation it will be a less than great sound. Line 6 (maker of POD) has a whole line of amps that have this function. You can go straight from amp to mixer and still use the amp to create "live" feedback during solos, etc.
If you are looking to get a guitar into a mixer, the DI is the way to go. If, on the other hand, you want the sound of your amp to get to a mixer, try a mic or an amp with a built in DI or cab sim.
Peace, Jim