Don't do it.
The Us428 is a DOG.
I'm sure at least half the people out there using the US428 are having some sort of high tech or low tech problem with the US428.
The features of the 428 are nice, but it's unstable, and is not all it's cracked up to be, in features. The Cubasis software is very limited, and the support for other programs is very sketchy, almost non existent.
Go look at
the US428 user's forum at
http://www.tascam.com and you'll see what I mean.
The support tech team at Tascam, despite their efforts, are troubleshooting their way around and around all these technical issues, and usually blaming the problem on everything else except the 428, but the problem staring them in the face is: The US428 is a DOG. It only works well, or 100% properly in the minority of cases.
Buy a nice used analog reel 8 track and mixer on ebay, and you'll be much happier, but if you're determined to want to record onto your computer, then do yourself a favor, and get an
M-Audio Delta 1010, and an outboard mixer, for a little more money than the US428, but guaranteed to be a lot more stable.