I got lucky with A/C for my studio.
When I decided to install central air conditioning in the house...the main goal was the upstairs, which is where the heat was the worst, and downstairs it's pretty cool except maybe in the two hottest months.
So as they were running the ducts, I asked the guy if he could run one all the way down to the studio...and at first it seemed like it would not be possible, but I showed them how they could run it through an existing closed porch, through the floor, and then a hard L-turn into the studio.
Ended being a piece of cake, and due to the extra length of duct...you can't even hear the A/C noise or are rushing in.
I then wrapped heavy insulation around the duct, then boxed it off, and by the time I was down with trim-n-paint....you couldn't even tell there was an A/C duct in there.
So my studio has great A/C and I can run my gear even in the dead of summer, and it's very comfortable and quiet. I just leave my studio door open, and the A/C return upstairs pulls the hot air out at the one end and the duct serves cool air at
the other.