For what it's worth, I have a Fender Twin "The Twin" model which has inputs for chanel switching or inputs for combining both the clean and drive chanels. I like using the combined chanel input. I usualy set the clean chanel first to get that classic Fender clean tone and volume I desire, then set the gain chanel to get the overdrive tones I like. Combining the two chanels allows me to push all the gain I want and still be able to hear distinct notes at the same time. You should be able to use both chanels (or more if you have them) of any amp if you have a splitter or a pedal with dual/stereo outputs without being concerned about damage to the amp.