Presonus might have driver problems, but like I said above the program itself doesn't talk directly to the interface (that's why they invented asio, to stop incompatibilities of programs talking to the interfaces. This is why ProTools always demanded certain hardware from a specific list.)
If that's the case, you should be finding Presonus users having problems no matter what the sequencer.
The link suggests using WDM. That should work too.
My basic philosophy is: Don't buy ANY music computer that doesn't have TexasInstruments firewire chips on it.
.....been using a Motu828mkII daisy-chained to Glyph firewire drive for 4 years on a Gateway laptop with built-in TI firewire with ZERO problems....