Just some suggestions- not a full "treatment..."
From my reading, if you took your idea to it's extreme, you would be sitting in the room, listening to music (or whatever) with over-the-ear headphones. Not a totally pointless idea, though, because you can then move back from that extreme. Near-field monitors would be your next step- I would run them with longish leads so I could move them around the room, setting them in positions I though would work, then leaving the room and checking which position resulted in the lowest sound levels in the rest of the house. For example, assume there is only one door leading from that room to the house, putting the speakers on the opposite wall- thus firing towards the door- might result in more sound in the rest of the house, than putting them on the same wall as the door and firing away from the door. Once you find the "quietest" placement, you can then work on soundproofing the room, and that task would be easier than if you used the "loudest" speaker placement.
Excess reverb usually kills intelligibility, so you would want to tune reflective surfaces in the room with Auralex foam panels, but not too much, lest you lose too many hi's and mid's and end up with a boomy, bass-y room.
You might want to install weatherstripping on the door leading to the rest of the house, too.