Hmm, considering the mic choices and if you have good good pre's, I would do this:
1st off, it may be easier with a single 12 inch cab because of phase differences, but a 4x12 should work great just with more time consuming placement.
You are wanting to get this in one pass if I understand correctly.
Get yourself the ususal 2 beta 57's, 421's or M88's or M160's (preferably m160) on the cone in a very tasty stereo location. Next, get yourself a piece or string or tape measure, and a pair of tight fitting closed back headphones OR an assistant to move shit around while you are in the control room.
Now, you have a U87 (you bastard) a 47 (you bastard) and a C12 (you bastard)... did I mention you are a bastard? 2 ways to accomplish this, the listening with phones and/or assistant way is the best. Move your U87 back and slightly to the left of the cabinet with the headphones on and the close miced mic on... as you move the mic through different areas, you will hear the phase go in and out. Move it to a location that sounds great and is in phase. It could be a foot away, but likely a few feet or more.
Pan this one hard left. Next, do the same with the C12 (you bastard) or the fet47 and get it equidistant from the center of the cone, only moving it out to the right of the cone. THis is where the tape measure or string will come in handy. Distance is very imporptant. Mess around with getting it in phase with the close mic, then with the opposite mic, and make sure the are all in phase together. Now you will have the close mics for definition panned left and right, and the mics further out to thicken things up in a sort of natural doubling effect. Phase is of utmost importance here. Try hard to get it right. You'll hear it when it is. Then blend the close stereo mics with the far stereo mics and it should wound quite nice for a single pass guitar recording.
Good luck, tell me if you try it and how you like it.
Another thing, roll off the woofiness, and dont let them totally suck all of the mids out or the guitar will disapear. The sound that is a great metal sound playing alone is not the sound that will be good in a mix (ususally). It will just disapear. Get some mids back in it, and a little less gain than you would expect to use, and it will still sound super heavy and way better.
Peace.