I do. I'm new to this forum, and decided to register here just to answer this question.
I've been using Linux for music making since about 2006. First it was just my drums that I did on Hydrogen in Linux, but since about 2011-2012 all of my music making has been Linux-based. It is a good platform for music making, and I am really happy with my studio. I have used a few distros over time, but lately I have been using AV Linux (AVL-MXE). I use Ardour as my DAW and I prefer native Linux plugins for effects and synths. There is a way to use Windows VSTs on Linux, but I have never bothered with that.