Cubase can do loads of things - but trying to recreate guitar tone, processing and effects, AND string effects, which are mechanical, and while looking simple, very difficult to replicate in electronics, frankly daft! One pitchblende might take all day, and be 'nearly' there, but the next note would need starting from scratch. Every pitchblend, pull off, hammer on, palm mute, left hand plucked note is individual. It would need considerable skill in manipulating cubase data, and I've been a Cubase user since Black and White Ataris days, and I don't think I could replicate the well known line from Parisienne walkways if I recorded it without the bends. Worse, to do the bends, you'd have to play it with the bends in your head, to play it properly.
Cubase is great for recording. Guitars are great to play. Best tool for the job is the rule. A guitar processor is best for the tones - you record what comes out. Cubase has some nice processor plugins. I don't use them - it's better to do this elsewhere.
Why on earth do you want to use Cubase for something it clearly isn't designed for?
To make Cubase do this properly, you need to be a good guitarist - and if you are one, then you would just play it!