FS tube and Vista has become a complete nightmare. I highly recommend staying away from this configuration. 2 software companies, the PC manufacturer, and presonus, all have failed to get the FS tube to record audio without significant issues. Seeing how i just upgraded my firepods with the FS tube and the vacuum tube pre, all non pro tools productions are at a stand still. Im going to try XP pro but all things considered, this is a very unfortunate situation for presonus. Their affordable gear hasnt gotten any better. Layouts may be well placed but the internal workings are poor at best. The Vista drivers are poorly written. Too bad.